Commonly Affected Mitochondrial Systems Disorders
For some, mitochondrial diseases are severely debilitating, often fatal and characteristically complex in nature. They are inherited through the mother, but can also be inherited from either parent. They can also be sporadic or induced by the environment.
In the United States, more than 50 million adults suffer from diseases in which mitochondrial dysfunction is involved. Mitochondrial dysfunction is found in diseases as diverse as cancer, infertility, diabetes, heart diseases, blindness deafness, kidney disease, liver disease, stroke, migraine, and the toxicity of HIV and other drugs. Mitochondrial dysfunction is also involved in aging and neurodegenerative diseases such as Parkinson and Alzheimer dementia.
It is estimated that of the 4 million children born each year in the United States, up to 4000 develop mitochondrial diseases. Many mitochondrial diseases are so new that they have not yet been mentioned in the medical textbooks or in to the medical literature. To date, there is no cure for mitochondrial diseases.
Get news and information about research
from NTI about how NTFactor is improving the quality of life for so
many people. By subscribing, you can receive updates to our clinical
research and new products.
 |
 |
 |
|
||
 |
|
 |
|
||
See mitoresearch.org for more information.
CPEO Chronic Progressive External Ophthalmoplegia, DEAF Maternally inherited Deafness or aminoglycoside-induced Deafness,
DEMCHO Dementia and Chorea, DMDF Diabetes Mellitus & Deafness, Exercise Intolerance, ESOC Epilepsy, Strokes, Optic atrophy, & Cognitive decline, FBSN Familial Bilateral Striatal Necrosis, FICP Fatal Infantile Cardiomyopathy Plus, a MELAS-associated cardiomyopathy, GER Gastrointestinal Reflux, KSS Kearns Sayre Syndrome, LDYT Leber's hereditary optic neuropathy and DYsTonia,
LHON Leber Hereditary Optic Neuropathy, LIMM Lethal Infantile Mitochondrial Myopathy, MDM Myopathy and Diabetes Mellitus,
MELAS Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes, MEPR Myoclonic Epilepsy and Psychomotor Regression, MERME MERRF/MELAS overlap disease, MERRF Myoclonic Epilepsy and Ragged Red Muscle Fibers, MHCM Maternally Inherited Hypertrophic CardioMyopathy, MICM Maternally Inherited Cardiomyopathy, MILS Maternally Inherited Leigh Syndrome,
Mitochondrial Encephalocardiomyopathy, Mitochondrial Encephalomyopathy, MM Mitochondrial Myopathy, MMC Maternal Myopathy and Cardiomyopathy, Multisystem Mitochondrial Disorder (myopathy, encephalopathy, blindness, hearing loss, peripheral neuropathy),
NARP Neurogenic muscle weakness, Ataxia, and Retinitis Pigmentosa; alternate phenotype at this locus is reported as Leigh Disease,
NIDDM Non-Insulin Dependent Diabetes Mellitus, PEM Progressive Encephalopathy, PME Progressive Myoclonus Epilepsy, RTT Rett Syndrome, SIDS Sudden Infant Death Syndrome, SNHL Sensorineural Hearing Loss, Varied Familial Presentation: clinical manifestations range from spastic paraparesis to multisystem progressive disorder & fatal cardiomyopathy to truncal ataxia, dysarthria, severe hearing loss, mental regression, ptosis, ophthalmoparesis, distal cyclones, & diabetes mellitus.
